While counterproductive work behaviors (CWB) are considered to be associated with both personal and situational antecedents, the relationship between these two factors is not entirely understood. Toward a better understanding of this issue, the present study examined the moderating effects of personality traits on the relationship between a specific situational stressor, abusive supervision, and organization-targeted counterproductive behaviors (CWB-O). The results found significant main effects for both abusive supervision and personality, as expected, as well as a significant interaction between them, whereby employees with low scores in conscientiousness, agreeableness, and/or emotional stability were more likely to engage in CWB-O in response to abusive behaviors from their supervisors.